N-tert-Butoxycarbonyl-D-glutamic acid 5-tert-butyl ester
BOC-D-GLU(OTBU)-OH
CAS: 104719-63-3
Molecular Formula: C14H25NO6
N-tert-Butoxycarbonyl-D-glutamic acid 5-tert-butyl ester - Names and Identifiers
N-tert-Butoxycarbonyl-D-glutamic acid 5-tert-butyl ester - Physico-chemical Properties
| Molecular Formula | C14H25NO6 |
| Molar Mass | 303.35 |
| Density | 1.121 |
| Boling Point | 449.8±40.0 °C(Predicted) |
| Appearance | Solid |
| BRN | 3594191 |
| pKa | 3.82±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| MDL | MFCD00076927 |
N-tert-Butoxycarbonyl-D-glutamic acid 5-tert-butyl ester - Risk and Safety
| WGK Germany | 3 |
| HS Code | 2924 19 00 |
N-tert-Butoxycarbonyl-D-glutamic acid 5-tert-butyl ester - Introduction
BOC-D-glutamic acid-5-tert-butyl ester (BOC-D-GLU(OTBU)-OH) is an organic compound with the following properties:
1. Appearance: white to yellowish solid.
2. Molecular formula: C16H25NO7.
3. Molecular weight: 343.4g/mol.
4. Melting Point: 64-66 ℃.
5. Solubility: Soluble in polar organic solvents such as dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF).
The main use of this compound is as a protective group in the field of organic synthesis. It can react with amino acid residues to form temporary protecting groups to prevent non-specific chemical reactions. In the synthesis of polypeptides or proteins, BOC-D-glutamic acid 5-tert-butyl ester can be used to protect the amine groups of glutamic acid residues.
The production method of BOC-D-glutamic acid -5-tert-butyl ester is generally obtained by a BOC-protected amino acid synthesis method. The specific steps include reacting D-glutamic acid with tert-butyl chloroformate (BOC-Cl) to produce BOC-D-glutamic acid -5-tert-butyl ester. The reaction process requires the use of alkaline solution and inert atmosphere for protection.
Regarding safety information, BOC-D-glutamic acid -5-tert-butyl ester is generally relatively safe under normal operating conditions. However, it can be irritating to the eyes, skin and respiratory tract. Necessary safety measures should be taken during operation, such as wearing protective glasses, gloves and respiratory protection equipment. Avoid inhaling dust of the compound or contact with skin. If necessary, operate in a well-ventilated laboratory environment and handle and store in accordance with safe operating instructions.
1. Appearance: white to yellowish solid.
2. Molecular formula: C16H25NO7.
3. Molecular weight: 343.4g/mol.
4. Melting Point: 64-66 ℃.
5. Solubility: Soluble in polar organic solvents such as dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF).
The main use of this compound is as a protective group in the field of organic synthesis. It can react with amino acid residues to form temporary protecting groups to prevent non-specific chemical reactions. In the synthesis of polypeptides or proteins, BOC-D-glutamic acid 5-tert-butyl ester can be used to protect the amine groups of glutamic acid residues.
The production method of BOC-D-glutamic acid -5-tert-butyl ester is generally obtained by a BOC-protected amino acid synthesis method. The specific steps include reacting D-glutamic acid with tert-butyl chloroformate (BOC-Cl) to produce BOC-D-glutamic acid -5-tert-butyl ester. The reaction process requires the use of alkaline solution and inert atmosphere for protection.
Regarding safety information, BOC-D-glutamic acid -5-tert-butyl ester is generally relatively safe under normal operating conditions. However, it can be irritating to the eyes, skin and respiratory tract. Necessary safety measures should be taken during operation, such as wearing protective glasses, gloves and respiratory protection equipment. Avoid inhaling dust of the compound or contact with skin. If necessary, operate in a well-ventilated laboratory environment and handle and store in accordance with safe operating instructions.
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: Boc-D-Glu(OtBu)-OH Visit Supplier Webpage Request for quotationCAS: 104719-63-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
N-tert-Butoxycarbonyl-D-glutamic acid 5-tert-butyl ester
3-AMINO-5-CHLORO-BENZONITRILE
Prasterone enanthate
(2-羟基-4-甲氧基苯基)硼酸
3-AMINO-5-CHLORO-BENZONITRILE
Prasterone enanthate
(2-羟基-4-甲氧基苯基)硼酸